Dr Sandrine Vessillier
Dr Sandrine Vessillier joined NIBSC in 2012. She has over 15-years’ experience in development of biotherapeutics (molecular engineering, production, purification and characterisation) and in preclinical testing using models of acute and chronic inflammation.
She performs research in cellular immunology to determine the mechanisms of pro-inflammatory mediator release from immune cells following exposure to biological medicines, eg. immunotherapies. She develops novel assays for predicting adverse responses to biotherapeutics.
She is also interested in the study of inflammation in arthritis disease to identify pathways/therapeutics that slow down inflammation and facilitate tissue repair without compromising the immune defence against infection. Her main interests include cytokines, monoclonal antibodies and matrix degrading enzymes.
She supervises the development of reference reagents for flow cytometry applications such as lyophilised cell standards for process controls for regenerative medicine, cell based diagnostics and immune monitoring of treatment efficacy.