Since joining NIBSC in 2002 Craig has worked in the haemostasis and fibrinolysis area of the Biotherapeutics Division. His main responsibilities are developing WHO International Standards for coagulation factors and related enzymes and inhibitors, and performing research that underpins these activities. He is also responsible for the official control authority batch release (OCABR) testing of Virus Inactivated (VI) Human Plasma.
With a background in molecular biology and protein biochemistry, Craig uses recombinant protein technologies and molecular techniques to study the enzyme kinetics of, and the interactions between, components of the fibrinolytic and coagulation pathways. His research interests have focused on the structure-function relationship of plasminogen activators used in thrombolytic therapy, and of bacterial virulence factors that hijack the mammalian haemostasis system. These include plasminogen activators, coagulases and associated cell surface receptors.
Principal Scientist, Haemostasis section, Division of Biotherapeutics
Coagulation factors and inhibitorsPlasminogen activatorsHaemostasis related bacterial virulence factorsFibrinolysis
SSC Coagulation Standards Standing Committee European Pharmacopoeia