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The National Institute for Biological Standards and Control

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  • Dr Craig Thelwell

Dr Craig Thelwell

Since joining the NIBSC in 2002 Craig has worked in the haemostasis and fibrinolysis area of the Biotherapeutics Division.  His main responsibilities are developing WHO International Standards for coagulation factors and related enzymes and inhibitors, and performing research that underpins these activities.  He is also responsible for the Independent Control Testing of Virus Inactivated (VI) Human Plasma.

With a background in molecular biology and protein biochemistry, Craig uses recombinant protein technologies and molecular techniques to study the enzyme kinetics of, and the interactions between, components of the fibrinolytic and coagulation pathways.  His research interests have focused on the structure-function relationship of plasminogen activators used in thrombolytic therapy, and of bacterial virulence factors that hijack the mammalian haemostasis system.  These include plasminogen activators, coagulases and associated cell surface receptors.

Current position

Principal Scientist, Haemostasis section, Division of Biotherapeutics

Areas of interest

Coagulation factors and inhibitors
Plasminogen activators
Haemostasis related bacterial virulence factors
Fibrinolysis

Qualifications

2000: PhD, Biochemistry and Genetics, University of Newcastle

1996: BSc, Biological Sciences, University of Birmingham

Representation on external committees

SSC Coagulation Standards Standing Committee 
European Pharmacopoeia

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