Skip to content
Medicines & Healthcare products Regulatory Agency
The National Institute for Biological Standards and Control

Confidence in biological medicines

  • Stay connected
  • Shopping Basket
  • Pay Now
  • Login / Register
  • Home
  • Products
  • Standardisation
  • Control testing
  • Science and research
  • Expert services
  • About us
  • Advanced therapies
  • Virology
  • Bacteriology
  • Biotherapeutics
  • Analytical sciences
  • Diagnostics
  • A to Z listing
  • Publications
  • Home  /  
  • Science and research  /  
  • Virology  /  
  • CJD resource centre  /  
  • Available samples  /  
  • WHO Reference Reagents  /  
  • NHBX0 - 0001  /  
  • Sequence Alignment
 

Sequence Alignment

 

The following alignment image image was generated after direct sequencing from PCR products using template genomic DNA extracted from the following homogenates;

 

Reference Code
Ref in image
Chr$
NHBX0/0001
Redcomposite
spCJD(M/M)
NHBX0/0002
Greencomposite
spCJD(M/M)
NHBY0/0003
Bluecomposite
nvCJD(M/M)
NHBX0/0004
Yellowcomposite
spCJD(M/V)
NHBZ0/0005
Clearcomposite
-ve ctrl(M/M)

 

 

Since these sequences represent data from a number of experiments (both + & -ve strand sequencing) the term composite is used to describe them.

 

mrna is a published prion sequence: AY008282.1  GI:11079225

 Example of section of MV trace
 

prion gene MM exampleExample of section of MM trace

 

Prion gene codon 129 VV traceExample of section of VV trace
 

 

  • Careers
  • Terms and conditions
  • Accessibility
  • Privacy notice
  • Cookies
  • Sitemap