Publications

NIBSC scientists produce a number of publications each year. Below we provide a complete list of our scientific publications between 2014-2025.

Publications by year
2025
2024
2023
2022
2021
2020
2019
2018
2017
2016
2015 
2014

2025

1. Ajay Castro S, Passmore IJ, Ndeh D, Shaw HA, Ruda A, Burns K, Thomson S, Nagar R, Alagesan K, Reglinski M, Lucas K, Abouelhadid S, Schwarz-Linek U, Mawas F, Widmalm G, Wren BW, Dorfmueller HC. Recombinant production platform for Group A Streptococcus glycoconjugate vaccines. NPJ Vaccines. 2025 Jan 22;10(1):16. doi:10.1038/s41541-025-01068-2
2. Alam M, Rana MJ, Salauddin A, Bentley E, Kamuyu G, Shill DK, Jahan S, Alam MM, Raihan MA, Rahman MZ, Raqib R, Azizi A, Rahman M. Development and Validation of a Standardized Pseudotyped Virus-Based Neutralization Assay for Assessment of Anti-Nipah Virus Neutralizing Activity in Candidate Nipah Vaccines. Vaccines (Basel). 2025 Jul 15;13(7). doi:10.3390/vaccines13070753
3. Alexa Dierig, Martina Kristof, Christina Dold, Elodie Lesne, Catpagavalli Asokanathan, Luke Blackwell, Barbara Bolgiano, Andrew R. Gorringe, Andrew J. Pollard, Kevin Markey, Christine S. Rollier. Adenoviral-vectored vaccine against Bordetella pertussis fimbrial antigen induces partial protection in a mouse model. Vaccine: X, 2025 Volume 24. doi.org/10.1016/j.jvacx.2025.100659.
4. Anwar S, Lamaudiere M, Hassall J, Dehinsilu J, Bhuller RK, Hold GL, Vázquez-Campos X, Mahnert A, Moissl-Eichinger C, Gallé B, Kainz G, Pjevac P, Hausmann B, Schwarz J, Kohl G, Berry D, Vancuren SJ, Allen-Vercoe E, Nielsen N, Sørensen N, Eklund A, Nielsen HB, Riedel R, Krause JL, Chang HD, Park S, Song HY, Seo H, Ul-Haq A, Kim S, Kwon Y, Park S, Soberon X, Silva-Herzog E, Verlouw JAM, Arp P, Jhamai M, Kraaij R, Geelen AR, Ducarmon QR, Smits WK, Kuijper EJ, Zwittink RD, van Best N, Penders J, Le G, Driessen C, Kool J, Shetty SA, Fuentes S, Demirci M, Yigin A, Whalley C, Beggs AD, Quince C, James R, Raguideau S, Gordon M, Mate R, Fritzsche M, Danckert NP, Blanco JM, Marchesi JR, Rauch M, Williamson RA, Van’t Wout AB, Kritz A, Rosecker S, Stevens R, Laws L, Sayavedra L, Romano S, Telatin A, Baker D, Narbad A, Servetas SL, Kralj JG, Forry SP, Hunter ME, Dootz JN, Jackson SA, Mason CE, Butler DJ, Mozsary C, Foox J, Damle N, Resh A, Busswitz A, Lenz P, Sontag S, Cross A, Sanchez C, Guo M, Olson K, Smith EA, La Reau AJ, Ward T, Kuersten S, Hyde F, Khrebtukova I, Schroth G, Rijpkema S, Amos GCA, Sergaki C. DNA reference reagents isolate biases in microbiome profiling: a global multi-lab study. mSystems. 2025 Nov 18;10(11):e0046625. doi:10.1128/msystems.00466-25
5. Aponte-Diaz D, Harris JM, Kang TE, Korboukh V, Sotoudegan MS, Gray JL, Yennawar NH, Moustafa IM, Macadam A, Cameron CE. Non-lytic spread of poliovirus requires the nonstructural protein 3CD. mBio. 2025 Jan 8;16(1):e0327624. doi:10.1128/mbio.03276-24
6. Arroyo Mühr LS, Eklund C, Lagheden C, Correa RM, Fellner MD, Picconi MA, Songur N, Gultekin M, Cuschieri K, Prétet JL, Lepiller Q, Baraquin A, Silling S, Søreng K, Stosic M, Presthus GK, Arbyn M, Peeters M, Gucht SV, Padalko E, Chin T, Kehoe K, Pereira AR, Redzic N, Vanden Broeck D, Molano M, Murray GL, Garland SM, Pinto LA, Wilkinson DE, Poljak M, Dillner J. The Human Papillomavirus (HPV) Laboratory e-Manual: A comprehensive guide for HPV testing and research. J Clin Virol. 2025 Aug;179:105834. doi:10.1016/j.jcv.2025.105834
7. Bentley EM, Richardson S, Atkinson E, Rigsby P, Emperador DM, Killip M, Page M, Mattiuzzo G. The development and evaluation of reference materials for Lassa virus molecular diagnostics. Frontiers in Virology. 2025 2025-November-03;Volume 5 - 2025. doi:10.3389/fviro.2025.1668042
8. Beresford NJ, De Benedetto G, Lockyer K, Gao F, Burkin K, Lalwani K, Bolgiano B. Further Insights into the Measurement of Free Polysaccharide in Meningococcal Conjugate Vaccines. Vaccines (Basel). 2025 Feb 9;13(2). doi:10.3390/vaccines13020167
9. Bottcher S, Kreibich J, Wilton T, Saliba V, Blomqvist S, Al-Hello H, Savolainen-Kopra C, Wieczorek M, Gad B, Krzysztoszek A, Pinto RM, Cabrerizo M, Bosch A, Saxentoff E, Diedrich S, Martin J. Detection of circulating vaccine-derived poliovirus type 2 (cVDPV2) in wastewater samples: a wake-up call, Finland, Germany, Poland, Spain, the United Kingdom, 2024. Euro Surveill. 2025 Jan;30(3). doi:10.2807/1560-7917.ES.2025.30.3.2500037
10. Bowyer AE, Khan M, Lawrence C, Macdonald S, Martin J, Platton S, Riddell A, Sanders J, Williams A, Williams S, Page A. The Laboratory Monitoring of Altuvoct (Efanesoctocog Alfa): Recommendations From the Laboratory Working Party of the United Kingdom Haemophilia Centres Doctor’s Organisation. Haemophilia. 2025 Nov 7;10.1111/hae.70152. doi:10.1111/hae.70152
11. Busby EJ, Lo Cascio L, Turon V, Whale AS, Huggett JF, Devonshire AS. Next-Generation Methods for More Precise Measurement of Cancer Genetic Changes. Clin Chem. 2025 Jul 4;71(7):725-7. doi:10.1093/clinchem/hvaf067
12. Butera D, Pijning AE, Avery NG, Coxon CH, Metcalfe C, Mimoun A, Lacroix-Desmazes S, Spiegel PC, Jr., Hogg PJ. Patient anti-FVIII drug antibodies bind preferentially to a subset of FVIII covalent states. Blood Adv. 2025 Aug 12;9(15):3706-15. doi:10.1182/bloodadvances.2025016474
13. Butler I, Turner O, Mohammed K, Akhtar M, Evans D, Lambourne J, Harris K, O’Sullivan DM, Sergaki C. Standardization of 16S rRNA gene sequencing using nanopore long read sequencing technology for clinical diagnosis of culture negative infections. Front Cell Infect Microbiol. 2025;15:1517208. doi:10.3389/fcimb.2025.1517208
14. Candido DDS, Dellicour S, Cooper LV, Prete CA, Jr., Jorgensen D, Uzzell CB, Voorman A, Lyons H, Klapsa D, Majumdar M, Arowolo K, Peak CM, Bandyopadhyay AS, Martin J, Grassly NC, Blake IM. Historical and current spatiotemporal patterns of wild and vaccine-derived poliovirus spread. Nat Microbiol. 2025 Dec;10(12):3148-61. doi:10.1038/s41564-025-02174-6
15. Castro SA, Thomson S, Shaw HA, Zorzoli A, Meyer BH, Reglinski M, McNeil M, Dorfmueller HC. Rhamnose polysaccharide-decorated outer membrane vesicles as a vaccine candidate targeting Group A Streptococcus from Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis. Vaccine X. 2025 Aug;25:100676. doi:10.1016/j.jvacx.2025.100676
16. Cherrington S, Hardy LJ, Maqbool A, Philippou H, Thelwell C. M1 protein from group A Streptococcus affects fibrin clot formation, structure, and fibrinolytic potential. Blood vessels, thrombosis & hemostasis. 2025 Nov;2(4):100094. doi:10.1016/j.bvth.2025.100094
17. Cnossen VM, Moreira PCL, Engelhardt OG, Samolej J, Groeneveld GH, Jochems SP, Huisman W, Pedersen GK, Wørzner K, Recek L, Piccini G, Trombetta CM, Aspelund A, Hoag A, Reiter M, Wick C, Muster T, Kamerling IMC. Development of an intranasal, universal influenza vaccine in an EU-funded public-private partnership: the FLUniversal consortium. Front Immunol. 2025;16:1568778. doi:10.3389/fimmu.2025.1568778
18. Costanzo A, Hogwood J. Establishment of a replacement batch for the Ph. Eur. Heparin low-molecular-mass for calibration CRS. Pharmeur Bio Sci Notes. 2025;2025:9-12. doi:10.82453/biosn-2025-02-en
19. Cowper B, Moore M, Burns C. Therapeutic glycoprotein hormones: Considerations for the use of in vitro alternatives to in vivo potency assays. J Pharm Biomed Anal. 2025 Sep 1;262:116895. doi:10.1016/j.jpba.2025.116895
20. Coxon C, Bell E, Adriaenssens E, Clark J, Edwards J, Gohir T, Hodges F, Jones J, Rees C, Sansom A, Smith D, Sutton M, Trippett C, Turner D. Interpretation guidance for MHRA regulatory considerations for phage therapeutic products. Microbiology (Reading). 2025 Nov;171(11). doi:10.1099/mic.0.001613
21. Da Silva AS, Anwar S, Park S, Park S, Goodfellow L, Sergaki C. The untapped potential of vaginal microbiome diagnostics for improving women’s health. Front Cell Infect Microbiol. 2025;15:1595182. doi:10.3389/fcimb.2025.1595182
22. Do Nascimento S, Theodosiou AA, Sergaki C. Microbiotoxicity: an under-recognised player in drug efficacy, toxicity, and health outcomes. npj antimicrobials and resistance. 2025 Dec 23;3(1):102. doi:10.1038/s44259-025-00165-5
23. Ekanger CT, Dinesh Kumar N, Koutstaal RW, Zhou F, Beukema M, Waldock J, Jochems SP, Mulder N, van Els C, Engelhardt OG, Mantel N, Buno KP, Brokstad KA, Engelsen AST, Cox RJ, Melgert BN, Huckriede ALW, van Kasteren PB. Comparison of air-liquid interface transwell and airway organoid models for human respiratory virus infection studies. Front Immunol. 2025;16:1532144. doi:10.3389/fimmu.2025.1532144
24. Etienne RAC, Takeuchi Y, Su X, Thanh NTK. Dengue diagnostics: from commercial tests to optical nanosensors. Nanoscale. 2025 Nov 20;17(45):25920-46. doi:10.1039/d5nr01842k
25. Hillman EBM, Baumgartner M, Carson D, Amos GCA, Wazir I, Khan HA, Khan MA, Rijpkema S, Walters JRF, Wellington EMH, Arasaradnam R, Lewis SJ. Changing Gastrointestinal Transit Time Alters Microbiome Composition and Bile Acid Metabolism: A Cross-Over Study in Healthy Volunteers. Neurogastroenterology and motility. 2025 Oct;37(10):e70075. doi:10.1111/nmo.70075
26. Hillman EBM, Carson D, Walters JRF, Fritzsche M, Mate R, Chappell KE, Chekmeneva E, Romero MG, Lewis SJ, Rijpkema S, Wellington EMH, Arasaradnam R, Amos GCA. Ruminococcus gnavus and Biofilm Markers in Feces From Primary Bile Acid Diarrhea Patients Indicate New Disease Mechanisms and Potential for Diagnostic Testing. Gastro hep advances. 2025;4(9):100712. doi:10.1016/j.gastha.2025.100712
27. Hogwood J, Gray E. Heparin: Over 100 Years of Anticoagulation. Handbook of experimental pharmacology. 2025 Dec 30;10.1007/164_2025_780. doi:10.1007/164_2025_780
28. Huseynov S, Saxentoff E, Diedrich S, Martin J, Wieczorek M, Cabrerizo M, Blomqvist S, Jorba J, Hagan J. Notes from the Field: Detection of Vaccine-Derived Poliovirus Type 2 in Wastewater - Five European Countries, September-December 2024. MMWR Morb Mortal Wkly Rep. 2025 Mar 6;74(7):122-4. doi:10.15585/mmwr.mm7407a4
29. Jasperse J, Wilson K, Akbar S, Hayden I, Naseem Q, Worthington A, Coglan A, Hewson M, Young A, Fang M, Liu Y, Darke J, Wong V, Godbole G, Hughes GJ. A local outbreak of iatrogenic botulism associated with cosmetic injections of botulinum neurotoxin-containing products, England, 2025. Euro Surveill. 2025 Oct;30(39). doi:10.2807/1560-7917.ES.2025.30.39.2500746
30. Jia H, Nowocin A, Burns C, Wadhwa M. Promoting Immune Response of Human Vascular Endothelial Cells by Bevacizumab: Insights into the Immune Supportive Role of Anti-VEGF Therapy. Int J Mol Sci. 2025 Jun 29;26(13). doi:10.3390/ijms26136280
31. Kempster SL, Ferguson D, Ham C, Hall J, Jenkins A, Giles E, Priestnall SL, Suarez-Bonnet A, Roques P, Le Grand R, Kandaswamy S, Sahastrabuddhe S, Hernandez LM, Chuasuwan S, Ahn HS, Kim DR, Wartel A, Zellweger RM, Berry N, Almond N. Inactivated Viral Vaccine BBV87 Protects Against Chikungunya Virus Challenge in a Non-Human Primate Model. Viruses. 2025 Apr 10;17(4). doi:10.3390/v17040550
32. Khatri B, Riese P, Shkarlet H, Mortier D, McShane H, Bowyer PW, Remarque E. Evaluation of 1(st) WHO anti-malaria reference reagent for competition ELISA harmonisation and development of ADAMSEL analytical platform. Biologicals. 2025 Nov;92:101850. doi:10.1016/j.biologicals.2025.101850
33. Liu W, Geard AF, Massaro G, Hughes MP, Aristorena M, Coombe-Tennant O, Xu L, Semenyuk O, Bush R, Te Vruchte D, Priestman D, Laban R, Veleva E, Heslegrave AJ, Zetterberg H, Platt FM, Smith AJ, Mole SE, Ali RR, Rahim AA. Brain-Directed AAV Gene Therapy Rescues a Mouse Model of the CLN5 Form of Neuronal Ceroid Lipofuscinosis Disease and Normalizes a Blood Plasma Biomarker of Neurodegeneration. Hum Gene Ther. 2025 Dec 16;10.1177/10430342251403448. doi:10.1177/10430342251403448
34. Marchesin F, Bentley EM, Mutuku F, Jeza V, Ndenga B, Kempster S, Dowall SD, Almond N, Wright E, Banyard AC, Buczkowski H, Elaldi N, Mirazimi A, Hewson R, Rose NJ, Takeuchi Y, Mattiuzzo G. A system to rapidly develop a bunyavirus pseudotyped virus neutralisation assay for pandemic preparedness. NPJ Vaccines. 2025 Nov 6;10(1):228. doi:10.1038/s41541-025-01278-8
35. McDonald JU, Hosken NA, Engelhardt OG. Assessing commutability of the first WHO International Standard for antiserum to respiratory syncytial virus. Vaccine. 2025 Aug 13;61:127430. doi:10.1016/j.vaccine.2025.127430
36. Meln I, Cnossen V, Corti N, Andeweg A, Baay M, Chiu C, Coia J, Cornely O, Cox RJ, Dasyam D, De Keersmaecker SCJ, Deming M, Waldock J, Engelhardt OG, Guo M, Haj-Ali Saflo O, Hensen A, Jeeninga R, Kolstoe S, Krut O, Kuijper EJ, Leal L, Mazur N, Mohn KGI, Morel S, Osterhaus A, Moreira AP, Smits WK, Sridhar S, Toomey D, van Gerven J, Vehreschild M, Yarzabal JP, Zimmer-Harwood P, Neels P, Olesen OF, Roestenberg M, Kamerling IMC. Regulatory workshop on standardisation of clinical procedures, endpoints and data robustness of human challenge studies - A stakeholder meeting report. Biologicals. 2025 May;90:101818. doi:10.1016/j.biologicals.2025.101818
37. Merrick B, Prossomariti D, Allen E, Bisnauthsing K, Kertanegara M, Sergaki C, Le Guennec AD, Delord M, Bell JT, Conte MR, Moyes DL, Shankar-Hari M, Douiri A, Goodman AL, Shawcross DL, Goldenberg SD. Faecal microbiota transplant to ERadicate gastrointestinal carriage of Antibiotic-Resistant Organisms (FERARO): A feasibility randomised controlled trial. J Infect. 2025 Jul;91(1):106504. doi:10.1016/j.jinf.2025.106504
38. Milne LK, Ajayakumar AAD, Holyland IL, Kotowska AM, Hogwood J, Gray E, Mulloy B, Merry CLR, Hook AL. Validation of the use of ToF-SIMS for analysis of glycosaminoglycans. Carbohydrate polymers. 2026 Jan 1;371:124415. doi:10.1016/j.carbpol.2025.124415
39. Moon K, Coxon C, Årdal C, Botgros R, Djebara S, Durno L, Fiore CR, Perrin JB, Dixon DM, Cavaleri M. Considerations and perspectives on phage therapy from the transatlantic taskforce on antimicrobial resistance. Nat Commun. 2025 Dec 4;16(1):10883. doi:10.1038/s41467-025-64608-3
40. Rathod V, Katke S, Patil S, Bhandare S, Kadam L, Gautam M, Gumma P, Kumar KM, Hassall L, Asokanathan C, Douglas-Bardsley A, Markey K, Gupta S, Rao H, Parekh S, Pujari P, Sharma H, Shaligram U, Gairola S. Quantitative bead-based multiplex assay for simultaneous determination of IgG concentrations of pertussis toxin, filamentous hemagglutinin, pertactin, diphtheria, tetanus, Haemophilus influenzae b, and hepatitis B in human serum samples. Front Immunol. 2025;16:1587567. doi:10.3389/fimmu.2025.1587567
41. Rose N. A new antibiotic is positive news-but it will take more to stay ahead of superbugs. Bmj. 2025 Oct 13;391:r2142. doi:10.1136/bmj.r2142
42. Sherry L, Bahar MW, Porta C, Fox H, Grehan K, Nasta V, Duyvesteyn HME, De Colibus L, Marsian J, Murdoch I, Ponndorf D, Kim SR, Shah S, Carlyle S, Swanson JJ, Matthews S, Nicol C, Lomonossoff GP, Macadam AJ, Fry EE, Stuart DI, Stonehouse NJ, Rowlands DJ. Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines. Nat Commun. 2025 Jan 18;16(1):831. doi:10.1038/s41467-025-56118-z
43. Sherry L, Grehan K, Bahar MW, Swanson JJ, Fox H, Matthews S, Carlyle S, Qin L, Porta C, Wilkinson S, Robb S, Clark N, Liddell J, Fry EE, Stuart DI, Macadam AJ, Rowlands DJ, Stonehouse NJ. Production of an immunogenic trivalent poliovirus virus-like particle vaccine candidate in yeast using controlled fermentation. NPJ Vaccines. 2025 Mar 31;10(1):64. doi:10.1038/s41541-025-01111-2
44. Simon CG, Jr., Bozenhardt EH, Celluzzi CM, Dobnik D, Grant ML, Lakshmipathy U, Nebel T, Peltier L, Ratcliffe A, Sherley JL, Stacey GN, Taghizadeh RR, Tan EHP, Vessillier S. Analysis of the measurements used as potency tests for the 31 US FDA-approved cell therapy products. J Transl Med. 2025 Mar 4;23(1):259. doi:10.1186/s12967-025-06253-4
45. Stickings P, Vipond C, Rigsby P, Micoli F, Rossi O, Mancini F, Conti V, Cohen D, Bialik A, Meron-Sudai S, Asato V, Clarkson KA, MacLennan CA, Kaminski RW. Cross-comparison study of three ELISA methodologies to measure Shigella Sonnei O-antigen serum IgG. mSphere. 2025 Oct 29;10(10):e0035625. doi:10.1128/msphere.00356-25
46. Suleman S, Alhaque S, Guo A, Zhang H, Payne A, Zahn M, Fawaz S, Khalifa MS, Jobling S, Hay D, Franco M, Fronza R, Wang W, Strobel-Freidekind O, Deichmann A, Takeuchi Y, Gil-Farina I, Klapwijk J, Perera S, Schmidt M, Themis M. (h)InGeTox: a human-based in vitro platform to evaluate lentivirus/host interactions that contribute to genotoxicity. Gene Ther. 2025 Dec;32(6):641-56. doi:10.1038/s41434-025-00550-9
47. Tounekti O, Prior S, Wassmer S, Xu J, Wong A, Fang X, Sonderegger I, Smeraglia J, Huleatt J, Loo L, Beaver C, DelCarpini J, Dessy F, Diebold S, Fiscella M, Garofolo F, Grimaldi C, Gupta S, Hou V, Irwin C, Jani D, Joseph J, Kalina W, Kar S, Kavita U, Lu Y, Marshall JC, Mayer C, Mora J, Nolan K, Peng K, Riccitelli N, Scully I, Seitzer J, Stern M, Wadhwa M, Xu Y, Verthelyi D, Sumner G, Clements-Egan A, Chen C, Gorovits B, Torri A, Baltrukonis D, Gunn G, Ishii-Watabe A, Kramer D, Kubiak RJ, Mullins G, Pan L, Partridge MA, Poetzl J, Rasamoelisolo M, Sirtori FR, Richards S, Saad OM, Shao W, Song Y, Song S, Staack RF, Wu B, Manangeeswaran M, Thacker S. 2024 White Paper on Recent Issues in Bioanalysis: Evolution of Immunogenicity Assessment beyond ADA/NAb; Regulated Genomic/NGS Assays; Hypersensitivity Reactions; Minimum Noise Reduction; False Positive Range; Modernized Vaccine Approaches; NAb/TAb Correlation (PART 3A - Recommendations on Advanced Strategies for Molecular Assays and Immunogenicity of Gene Therapy, Cell Therapy, Vaccine; Biotherapeutics Immunogenicity Assessment & Clinical Relevance PART 3B - Regulatory Agencies’ Input on Immunogenicity/Technologies of Biotherapeutics, Gene, Cell & Vaccine Therapies). Bioanalysis. 2025 Feb;17(3):105-49. doi:10.1080/17576180.2024.2439229
48. Tounekti O, Shubow S, Wassmer S, Van Tuyl A, Yang L, Gong B, Abhari MR, Kalina W, Myler H, DelCarpini J, Escobar D, Fiscella M, Gorovits B, Gupta S, Irvin SC, Irwin C, Jankowski W, Jawa V, Karauzum H, Kerridge C, Lu Y, Mayer C, McGregor J, Melton A, Murphy R, Nanra J, Nowocin A, Partridge MA, Prior S, Sauna Z, Scott B, Seitzer J, Stern M, Sugimoto H, Taylor M, Wong A, Xiao W, Xu Y, Yang TY, Yuill D, Kubiak RJ, Thway T, Gunn G, Pelto R, Sumner G, Baltrukonis D, Dholakiya SL,(1) Dogmanits S, Garofolo F, Jadhav M, Kramer D, Meyer E, Mohapatra S, Mozaffari R, Peng K, Pine S, Poetzl J, Rasamoelisolo M, Shao W, Staack RF, Swanson S, Taqui A, Vauleon S, Wang Y, Wen Y. 2025 White Paper on Recent Issues in Bioanalysis: Redosing Patients with AAV Gene Therapy; CRS Immunogenicity Risk; Shedding Assays; NHP Studies Immunogenicity; CMC vs Bioanalytical Assays; Artificial Intelligence-Powered Genomic Pipelines for NGS (PART 3A - Recommendations on Gene, Cell, and Vaccine Therapies Immunogenicity & Technologies; Biotherapeutics & Biosimilars Immunogenicity Assessment & Clinical Relevance PART 3B - Regulatory Agencies’ Input on Immunogenicity/Technologies of Biotherapeutics, Gene, Cell & Vaccine Therapies). Bioanalysis. 2025 Nov;17(22):1365-409. doi:10.1080/17576180.2025.2586976
49. Wadhwa M, Cludts I, Atkinson E, Rigsby P. The first WHO reference panel for Infliximab anti-drug antibodies: a step towards harmonizing therapeutic drug monitoring. Front Immunol. 2025;16:1550655. doi:10.3389/fimmu.2025.1550655
50. Ward-Deitrich CL, Nehete S, Del Castillo Busto ME, Hill S, Robertson FP, Luckau L, Hannemann H, Fox B, Goenaga-Infante H. Species-Specific Isotope Dilution Methodology for the SI Traceable Quantification of Serum Human Ferritin Light Chain (FTL). Anal Chem. 2025 Nov 25;97(46):25643-54. doi:10.1021/acs.analchem.5c04597
51. Wijesekara PS, Malik K, Matejtschuk P, Smith G. An Application for Through-Vial Impedance Spectroscopy (TVIS) in the Qualification of the Pirani-Gauge Assessment of the Ice Sublimation Endpoint. Pharmaceutics. 2025 Nov 29;17(12). doi:10.3390/pharmaceutics17121542
52. Yousif MD, Kubajewska I, Mawas F, Murdan S. Correlations Between Rheology, In Situ Mucosal Retention and In Vivo Immunogenicity Reveal the Potential and Limitations of Mucoadhesive Excipients for Sublingual Vaccine Delivery. Pharmaceutics. 2025 Nov 11;17(11). doi:10.3390/pharmaceutics17111456

2024

2023

2022

1. Tedcastle A, Wilton T, Pegg E, Klapsa D, Bujaki E, Mate R, Fritzsche M, Majumdar M, Martin J. Detection of Enterovirus D68 in Wastewater Samples from the UK between July and November 2021: Viruses. 2022 Jan 13;14(1):143. doi: 10.3390/v14010143.35062346
2. Chan WY, Entwisle C, Ercoli G, Ramos-Sevillano E, McIlgorm A, Cecchini P, Bailey C, Lam O, Whiting G, Green N, Goldblatt D, Wheeler JX, Brown JS. A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge: Infect Immun. 2022 Jan 25;90(1):e0084618a. doi: 10.1128/IAI.00846-18a. Epub 2018 Dec 10.35076289
3. Sharp G, Poles A, Studholme L. A first WHO reference reagent for the detection of anti-human platelet antigen-15b: Vox Sang. 2022 Feb;117(2):275-281. doi: 10.1111/vox.13167. Epub 2021 Jun 23.34164825
4. Wheeler JX, Thelwell C, Rigsby P, Whiting G. Quantitation of thrombin-activatable fibrinolysis inhibitor in human plasma by isotope dilution mass spectrometry: Anal Biochem. 2022 Feb 1;638:114413. doi: 10.1016/j.ab.2021.114413. Epub 2021 Oct 10.34644544
5. Hassall J, Sergaki C. Microbiome therapies: why we are not there yet: Prescriber. 2022 Feb;15;33:39-40. doi.org/10.1002/psb.1972
6. Bevan S, Longstaff C. Is it possible to make a common reference standard for D-dimer measurements? Communication from the ISTH SSC Subcommittee on Fibrinolysis: J Thromb Haemost. 2022 Feb;20(2):498-507. doi: 10.1111/jth.15555. Epub 2021 Nov 24.34653304
7.  Raut S, Katona É, Riches-Duit A, Coxon C, Muszbek L, Schroeder V, Rigsby P. An international collaborative study to assign value for Total Factor XIII-B Subunit Antigen to the WHO 1st International Standard for Factor XIII Plasma, (02/206): Communication from the ISTH SSC Subcommittee on Factor XIII and Fibrinogen: J Thromb Haemost. 2022 Feb;20(2):525-531. doi: 10.1111/jth.15596. Epub 2021 Nov 30.34784091
8. Zhu F, Althaus T, Tan CW, Costantini A, Chia WN, Van Vinh Chau N, Van Tan L, Mattiuzzo G, Rose NJ, Voiglio E, Wang LF. WHO international standard for SARS-CoV-2 antibodies to determine markers of protection: Lancet Microbe. 2022 Feb;3(2):e81-e82. doi: 10.1016/S2666-5247(21)00307-4. Epub 2021 Dec 3.34901897
9. Thorne LG, Bouhaddou M, Reuschl AK, Zuliani-Alvarez L, Polacco B, Pelin A, Batra J, Whelan MVX, Hosmillo M, Fossati A, Ragazzini R, Jungreis I, Ummadi M, Rojc A, Turner J, Bischof ML, Obernier K, Braberg H, Soucheray M, Richards A, Chen KH, Harjai B, Memon D, Hiatt J, Rosales R, McGovern BL, Jahun A, Fabius JM, White K, Goodfellow IG, Takeuchi Y, Bonfanti P, Shokat K, Jura N, Verba K, Noursadeghi M, Beltrao P, Kellis M, Swaney DL, García-Sastre A, Jolly C, Towers GJ, Krogan NJ. Evolution of enhanced innate immune evasion by SARS-CoV-2: Nature. 2022 Feb;602(7897):487-495. doi: 10.1038/s41586-021-04352-y. Epub 2021 Dec 23.34942634
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61. Shaw AG, Majumdar M, Troman C, O’Toole A, Benny B, Abraham D, Praharaj I, Kang G, Sharif S, Alam MM et al: Rapid and Sensitive Direct Detection and Identification of Poliovirus from Stool and Environmental Surveillance Samples by Use of Nanopore Sequencing. J Clin Microbiol 2020, 58(9) http://dx.doi.org/10.1128/JCM.00920-20
62. Shaw HA, Preston MD, Vendrik KEW, Cairns MD, Browne HP, Stabler RA, Crobach MJT, Corver J, Pituch H, Ingebretsen A et al: The recent emergence of a highly related virulent Clostridium difficile clade with unique characteristics. Clin Microbiol Infect 2020, 26(4):492-498 http://dx.doi.org/10.1016/j.cmi.2019.09.004
63. Sung JL, Hawkins JR: A highly sensitive internally-controlled real-time PCR assay for mycoplasma detection in cell cultures. Biologicals 2020, 64:58-72 http://dx.doi.org/10.1016/j.biologicals.2019.12.007
64. Thachil J, Longstaff C, Favaloro EJ, Lippi G, Urano T, Kim PY, Thrombosis SSCSoFotISo, Haemostasis: The need for accurate D-dimer reporting in COVID-19: Communication from the ISTH SSC on fibrinolysis. J Thromb Haemost 2020, 18(9):2408-2411 http://dx.doi.org/10.1111/jth.14956
65. Thelwell C, Hogwood J, Daniels S, Rigsby P: A new WHO reference reagent for activated blood coagulation factor X (FXa), human (15/102). J Thromb Haemost 2020, 18(1):255-257 http://dx.doi.org/10.1111/jth.14623
66. Tzu-Yu Weng HY, Kutub Mahmood, Javier Martin, and Min-Shi Lee: Workshop Report on Global Harmonization of Enterovirus Vaccines. Emerging Infectious Diseases 2020, 26(4) https://doi.org/10.3201/eid2604.191273
67. Vidana B, Brookes SM, Everett HE, Garcon F, Nunez A, Engelhardt O, Major D, Hoschler K, Brown IH, Zambon M: Inactivated pandemic 2009 H1N1 influenza A virus human vaccines have different efficacy after homologous challenge in the ferret model. Influenza Other Respir Viruses 2020,  http://dx.doi.org/10.1111/irv.12784
68. Wadhwa M, Kang HN, Jivapaisarnpong T, procedures: WHO implementation workshop on guidelines on procedures and data requirements for changes to approved biotherapeutic products, Seoul, Republic of Korea, 25-26 June 2019. Biologicals 2020, 65:50-59 http://dx.doi.org/10.1016/j.biologicals.2019.12.008
69. Wadhwa M, Rigsby P, Behr-Gross ME: Collaborative study for the establishment of Infliximab Biological Reference Preparation Batch 1. Pharmeur Bio Sci Notes 2020, 2020:49-52
70. Warre-Cornish K, Perfect L, Nagy R, Duarte RRR, Reid MJ, Raval P, Mueller A, Evans AL, Couch A, Ghevaert C et al: Interferon-gamma signaling in human iPSC-derived neurons recapitulates neurodevelopmental disorder phenotypes. Sci Adv 2020, 6(34):eaay9506 http://dx.doi.org/10.1126/sciadv.aay9506
71. Wenzel EV, Bosnak M, Tierney R, Schubert M, Brown J, Dubel S, Efstratiou A, Sesardic D, Stickings P, Hust M: Human antibodies neutralizing diphtheria toxin in vitro and in vivo. Sci Rep 2020, 10(1):571 http://dx.doi.org/10.1038/s41598-019-57103-5
72. Whiting G, Vipond C, Facchetti A, Chan H, Wheeler JX: Measurement of surface protein antigens, PorA and PorB, in Bexsero vaccine using quantitative mass spectrometry. Vaccine 2020, 38(6):1431-1435 http://dx.doi.org/10.1016/j.vaccine.2019.11.082
73. Williams SC, Gray E: Activity measurements of dalcinonacog alfa. Haemophilia 2020, 26(2):346-353 http://dx.doi.org/10.1111/hae.13949
74. Wilmot HV, Rakowski K, Gray E: The traceability of commercial plasma calibrators to the plasma International Standards for factor VIII and factor IX. Int J Lab Hematol 2020,  http://dx.doi.org/10.1111/ijlh.13277
75. Yeh MT, Bujaki E, Dolan PT, Smith M, Wahid R, Konz J, Weiner AJ, Bandyopadhyay AS, Van Damme P, De Coster I et al: Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence. Cell Host & Microbe 2020, 27(5):736 http://dx.doi.org/10.1016/j.chom.2020.04.003
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77. Zaman SM, Howie SR, Ochoge M, Secka O, Bah A, Baldeh I, Sanneh B, Darboe S, Ceesay B, Camara HB et al: Impact of routine vaccination against Haemophilus influenzae type b in The Gambia: 20 years after its introduction. J Glob Health 2020, 10(1):010416 http://dx.doi.org/10.7189/jogh.10.010416

2019

1. Almond N, Berry N, Stebbings R, Preston M, Ham C, Page M, Ferguson D, Rose N, Li B, Mee ET et al: Vaccination of Macaques with DNA Followed by Adenoviral Vectors Encoding Simian Immunodeficiency Virus (SIV) Gag Alone Delays Infection by Repeated Mucosal Challenge with SIV. J Virol 2019, 93(21) http://dx.doi.org/10.1128/JVI.00606-19 
2. Ashiru O, Esteso G, Garcia-Cuesta EM, Castellano E, Samba C, Escudero-Lopez E, Lopez-Cobo S, Alvarez-Maestro M, Linares A, Ho MM et al: BCG Therapy of Bladder Cancer Stimulates a Prolonged Release of the Chemoattractant CXCL10 (IP10) in Patient Urine. Cancers (Basel) 2019, 11(7) http://dx.doi.org/10.3390/cancers11070940 
3. Awanye AM, Chang CM, Wheeler JX, Chan H, Marsay L, Dold C, Rollier CS, Bird LE, Nettleship JE, Owens RJ et al: Immunogenicity profiling of protein antigens from capsular group B Neisseria meningitidis. Sci Rep 2019, 9(1):6843 http://dx.doi.org/10.1038/s41598-019-43139-0 
4. Barkoff AM, Mertsola J, Pierard D, Dalby T, Hoegh SV, Guillot S, Stefanelli P, van Gent M, Berbers G, Vestrheim D et al: Pertactin-deficient Bordetella pertussis isolates: evidence of increased circulation in Europe, 1998 to 2015. Euro Surveill 2019, 24(7) http://dx.doi.org/10.2807/1560-7917.ES.2019.24.7.1700832 
5. Berry N, Ferguson D, Ham C, Hall J, Jenkins A, Giles E, Devshi D, Kempster S, Rose N, Dowall S et al: High susceptibility, viral dynamics and persistence of South American Zika virus in New World monkey species. Sci Rep 2019, 9(1):14495 http://dx.doi.org/10.1038/s41598-019-50918-2 
6. Bhide Y, Dong W, Gribonika I, Voshart D, Meijerhof T, de Vries-Idema J, Norley S, Guilfoyle K, Skeldon S, Engelhardt OG et al: Cross-Protective Potential and Protection-Relevant Immune Mechanisms of Whole Inactivated Influenza Virus Vaccines Are Determined by Adjuvants and Route of Immunization. Front Immunol 2019, 10:646 http://dx.doi.org/10.3389/fimmu.2019.00646 
7. Booth B, Stevenson L, Pillutla R, Buonarati M, Beaver C, Fraier D, Garofolo F, Haidar S, Islam R, James C et al: White Paper On Recent Issues in Bioanalysis: FDA BMV Guidance, ICH M10 BMV Guideline and Regulatory Inputs (Part 2 - Recommendations on 2018 FDA BMV Guidance, 2019 ICH M10 BMV Draft Guideline and Regulatory Agencies’ Input on Bioanalysis, Biomarkers and Immunogenicity). Bioanalysis 2019, 11(23):2099-2132 http://dx.doi.org/10.4155/bio-2019-0270 
8. Borsetto C, Amos GCA, da Rocha UN, Mitchell AL, Finn RD, Laidi RF, Vallin C, Pearce DA, Newsham KK, Wellington EMH: Microbial community drivers of PK/NRP gene diversity in selected global soils. Microbiome 2019, 7(1):78 http://dx.doi.org/10.1186/s40168-019-0692-8 
9. Bricogne C, Fine M, Pereira PM, Sung J, Tijani M, Wang Y, Henriques R, Collins MK, Hilgemann DW: Author Correction: TMEM16F activation by Ca(2+) triggers plasma membrane expansion and directs PD-1 trafficking. Sci Rep 2019, 9(1):7705 http://dx.doi.org/10.1038/s41598-019-43808-0 
10. Bricogne C, Fine M, Pereira PM, Sung J, Tijani M, Wang Y, Henriques R, Collins MK, Hilgemann DW: TMEM16F activation by Ca(2+) triggers plasma membrane expansion and directs PD-1 trafficking. Sci Rep 2019, 9(1):619 http://dx.doi.org/10.1038/s41598-018-37056-x 
11. Brown JC, Barclay WS, Galiano M, Harvey R: Passage of influenza A/H3N2 viruses in human airway cells removes artefactual variants associated with neuraminidase-mediated binding. J Gen Virol 2019,  http://dx.doi.org/10.1099/jgv.0.001348 
12. Chan WY, Entwisle C, Ercoli G, Ramos-Sevillano E, McIlgorm A, Cecchini P, Bailey C, Lam O, Whiting G, Green N et al: A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge. Infect Immun 2019, 87(3) http://dx.doi.org/10.1128/IAI.00846-18 
13. Chaskiel L, Bristow AD, Bluthe RM, Dantzer R, Blomqvist A, Konsman JP: Interleukin-1 reduces food intake and body weight in rat by acting in the arcuate hypothalamus. Brain Behav Immun 2019, 81:560-573 http://dx.doi.org/10.1016/j.bbi.2019.07.017 
14. Chen LM, Donis RO, Suarez DL, Wentworth DE, Webby R, Engelhardt OG, Swayne DE: Biosafety risk assessment for production of candidate vaccine viruses to protect humans from zoonotic highly pathogenic avian influenza viruses. Influenza Other Respir Viruses 2019,  http://dx.doi.org/10.1111/irv.12698 
15. Civoli F, Kasinath A, Cai XY, Wadhwa M, Exley A, Oldfield P, Alvandkouhi S, Schaffar G, Chappell J, Bowsher R et al: Recommendations for the Development and Validation of Immunogenicity Assays in Support of Biosimilar Programs. AAPS J 2019, 22(1):7 http://dx.doi.org/10.1208/s12248-019-0386-y 
16. Cowper B, Burns C, Bristow AF, Letallec D, Costanzo A: Assessment of methods for determination of glycan composition of erythropoietin. Pharmeur Bio Sci Notes 2019, 2019:34-53  
17. Cowper B, Hockley J, Partridge K, Ferguson J, Rigsby P, Burns C: The first World Health Organization International Standard for in vitro biological activity of darbepoetin. Biologicals 2019,  http://dx.doi.org/10.1016/j.biologicals.2019.12.004 
18. Cowper B, Laven M, Hakkarainen B, Mulugeta E: Glycan analysis of erythropoiesis-stimulating agents. J Pharm Biomed Anal 2019, 180:113031 http://dx.doi.org/10.1016/j.jpba.2019.113031 
19. Coxon CH, Longstaff C, Burns C: Applying the science of measurement to biology: Why bother? PLoS Biol 2019, 17(6):e3000338 http://dx.doi.org/10.1371/journal.pbio.3000338 
20. De Leoz MLA, Duewer DL, Fung A, Liu L, Yau HK, Potter O, Staples GO, Furuki K, Frenkel R, Hu Y et al: NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods. Mol Cell Proteomics 2019,  http://dx.doi.org/10.1074/mcp.RA119.001677 
21. De Niz M, Nacer A, Frischknecht F: Intravital microscopy: Imaging host-parasite interactions in the brain. Cell Microbiol 2019, 21(5):e13024 http://dx.doi.org/10.1111/cmi.13024 
22. Douglas-Bardsley A, Asokanathan C, Tierney S, Hockley J, Markey K: Collaborative study for the calibration of the replacement International Standard for pertussis toxin for use in histamine sensitisation and CHO cell clustering assays. Biologicals 2019, 62:85-92 http://dx.doi.org/10.1016/j.biologicals.2019.09.001 
23. Duralliu A, Matejtschuk P, Dubey S, Koroma H, Gubinelli F, Williams DR: The influence of the closure format on the storage stability and moisture content of freeze-dried influenza antigen. Vaccine 2019, 37(32):4485-4490 http://dx.doi.org/10.1016/j.vaccine.2019.06.070 
24. Duralliu A, Matejtschuk P, Williams DR: Measuring the specific surface area (SSA) of freeze-dried biologics using inverse gas chromatography. Eur J Pharm Biopharm 2019, 142:216-221 http://dx.doi.org/10.1016/j.ejpb.2019.06.026 
25. Evangelopoulos D, Prosser GA, Rodgers A, Dagg BM, Khatri B, Ho MM, Gutierrez MG, Cortes T, de Carvalho LPS: Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes. Nat Commun 2019, 10(1):4177 http://dx.doi.org/10.1038/s41467-019-12074-z 
26. Faleye TOC, Adewumi OM, Klapsa D, Majumdar M, Martin J, Adeniji JA: Genome Sequences of Two Dual-Serotype-Specific Echovirus 20 Strains from Nigeria. Microbiol Resour Announc 2019, 8(43) http://dx.doi.org/10.1128/MRA.00894-19 
27. Faulds-Pain A, Shaw HA, Terra VS, Kellner S, Brockmeier SL, Wren BW: The Streptococcos suis sortases SrtB and SrtF are essential for disease in pigs. Microbiology 2019, 165(2):163-173 http://dx.doi.org/10.1099/mic.0.000752 
28. Ferguson J, Burns CJ, Regourd E, Costanzo A: Collaborative study for the establishment of erythropoietin BRP batch 5. Pharmeur Bio Sci Notes 2019, 2019:27-33  
29. Ferguson J, Patel D, Atkinson E, Rigsby P, Burns C: Continued provision of WHO International Standards for total and free PSA: Content and commutability of replacement preparations. Clin Biochem 2019, 71:58-66 http://dx.doi.org/10.1016/j.clinbiochem.2019.07.007 
30. Fitzpatrick M, Ho MM, Clark S, Dagg B, Khatri B, Lanni F, Williams A, Brennan M, Laddy D, Walker B: Comparison of pellicle and shake flask-grown BCG strains by quality control assays and protection studies. Tuberculosis (Edinb) 2019, 114:47-53 http://dx.doi.org/10.1016/j.tube.2018.10.013 
31. Fox B, Hockley J, Studholme L: The British Standard for (European Conformity[CE] Marked) Anti-D: Its rarely discussed but important role in quantitating anti-D in patient plasma. Transfus Med 2019,  http://dx.doi.org/10.1111/tme.12649 
32. Fox B, Sharp G, Atkinson E, Roberts G, Rigsby P, Studholme L: The third international standard for anti-D immunoglobulin: international collaborative study to evaluate candidate preparations. Vox Sang 2019, 114(7):740-748 http://dx.doi.org/10.1111/vox.12822 
33. Fox BJ, Hockley J, Rigsby P, Dolman C, Meroni PL, Ronnelid J: A WHO Reference Reagent for lupus (anti-dsDNA) antibodies: international collaborative study to evaluate a candidate preparation. Ann Rheum Dis 2019, 78(12):1677-1680 http://dx.doi.org/10.1136/annrheumdis-2019-215845 
34. Gao F, Swann C, Rigsby P, Rijpkema S, Lockyer K, Logan A, Bolgiano B, Vi ISWG: Evaluation of two WHO First International Standards for Vi polysaccharide from Citrobacter freundii and Salmonella enterica subspecies enterica serovar Typhi. Biologicals 2019, 57:34-45 http://dx.doi.org/10.1016/j.biologicals.2018.11.004 
35. Gao J, Couzens L, Burke DF, Wan H, Wilson P, Memoli MJ, Xu X, Harvey R, Wrammert J, Ahmed R et al: Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies. mBio 2019, 10(2) http://dx.doi.org/10.1128/mBio.00307-19 
36. Govind S, Hockley J, Morris C, Almond N, Collaborative Study G: The development and establishment of the 1st WHO BKV International Standard for nucleic acid based techniques. Biologicals 2019, 60:75-84 http://dx.doi.org/10.1016/j.biologicals.2019.04.004 
37. Gray E, Kitchen S, Bowyer A, Chowdary P, Jenkins PV, Murphy P, Platton S, Riddell A, Lester W: Laboratory measurement of factor replacement therapies in the treatment of congenital haemophilia: A United Kingdom Haemophilia Centre Doctors’ Organisation guideline. Haemophilia 2019,  http://dx.doi.org/10.1111/hae.13907 
38. Gu B, Piebalgs A, Huang Y, Longstaff C, Hughes AD, Chen R, Thom SA, Xu XY: Mathematical Modelling of Intravenous Thrombolysis in Acute Ischaemic stroke: Effects of Dose Regimens on Levels of Fibrinolytic Proteins and Clot Lysis Time. Pharmaceutics 2019, 11(3) http://dx.doi.org/10.3390/pharmaceutics11030111 
39. Gu B, Piebalgs A, Huang Y, Roi D, Lobotesis K, Longstaff C, Hughes AD, Chen R, Thom SA, Xu XY: Computational simulations of thrombolysis in acute stroke: Effect of clot size and location on recanalisation. Med Eng Phys 2019, 73:9-17 http://dx.doi.org/10.1016/j.medengphy.2019.07.014 
40. Gurjar SA, Wheeler JX, Wadhwa M, Thorpe R, Kimber I, Derrick JP, Dearman RJ, Metcalfe C: The impact of thioredoxin reduction of allosteric disulfide bonds on the therapeutic potential of monoclonal antibodies. J Biol Chem 2019, 294(51):19616-19634 http://dx.doi.org/10.1074/jbc.RA119.010637 
41. Harvey R, Mattiuzzo G, Hassall M, Sieberg A, Muller MA, Drosten C, Rigsby P, Oxenford CJ, Caly L, Li C et al: Comparison of Serologic Assays for Middle East Respiratory Syndrome Coronavirus. Emerging Infectious Diseases 2019, 25(10):1878-1883 http://dx.doi.org/10.3201/eid2510.190497 
42. Hassan H, Diebold SS, Smyth LA, Walters AA, Lombardi G, Al-Jamal KT: Application of carbon nanotubes in cancer vaccines: Achievements, challenges and chances. J Control Release 2019, 297:79-90 http://dx.doi.org/10.1016/j.jconrel.2019.01.017 
43. Hayes A, Nguyen D, Andersson M, Anton A, Bailly JL, Beard S, Benschop KSM, Berginc N, Blomqvist S, Cunningham E et al: A European multi-centre evaluation of detection and typing methods for human enteroviruses and parechoviruses using RNA transcripts. J Med Virol 2019,  http://dx.doi.org/10.1002/jmv.25659 
44. Hellen N, Pinto Ricardo C, Vauchez K, Whiting G, Wheeler JX, Harding SE: Proteomic Analysis Reveals Temporal Changes in Protein Expression in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes In Vitro. Stem Cells Dev 2019, 28(9):565-578 http://dx.doi.org/10.1089/scd.2018.0210 
45. Hitri K, Kuttel MM, De Benedetto G, Lockyer K, Gao F, Hansal P, Rudd TR, Beamish E, Rijpkema S, Ravenscroft N et al: O-acetylation of typhoid capsular polysaccharide confers polysaccharide rigidity and immunodominance by masking additional epitopes. Vaccine 2019, 37(29):3866-3875 http://dx.doi.org/10.1016/j.vaccine.2019.05.050 
46. Howard C, Hill E, Kreuzer M, Mali P, Masiero E, Slater A, Sgamma T: DNA Authentication of St John’s Wort (Hypericum perforatum L.) Commercial Products Targeting the ITS Region. Genes (Basel) 2019, 10(4) http://dx.doi.org/10.3390/genes10040286 
47. Huang Y, Yu L, Ren J, Gu B, Longstaff C, Hughes AD, Thom SA, Xu XY, Chen R: An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy. J Control Release 2019, 300:1-12 http://dx.doi.org/10.1016/j.jconrel.2019.02.033 
48. Hubbard AR, Haberichter SL, ISTH SSCsovWfot: Establishment of an International Reference Reagent for standardization of von Willebrand factor binding to recombinant glycoprotein Ib (VWF:GPIbM and VWF:GPIbR): Official Communication of the SSC. J Thromb Haemost 2019, 17(6):1003-1005 http://dx.doi.org/10.1111/jth.14429 
49. Hubbard AR, Thelwell C, Rigsby P, Subcommittee on Factor Viii FIX, Rare Coagulation D: Establishment of the WHO 2nd International Standard Factor V, plasma (16/374): communication from the SSC of the ISTH. J Thromb Haemost 2019, 17(4):695-697 http://dx.doi.org/10.1111/jth.14403
50. Hussain S, Turnbull ML, Pinto RM, McCauley JW, Engelhardt OG, Digard P: Segment 2 from influenza A(H1N1) 2009 pandemic viruses confers temperature-sensitive haemagglutinin yield on candidate vaccine virus growth in eggs that can be epistatically complemented by PB2 701D. J Gen Virol 2019, 100(7):1079-1092 http://dx.doi.org/10.1099/jgv.0.001279 
51. Hussain S, Turnbull ML, Wise HM, Jagger BW, Beard PM, Kovacikova K, Taubenberger JK, Vervelde L, Engelhardt OG, Digard P: Mutation of Influenza A Virus PA-X Decreases Pathogenicity in Chicken Embryos and Can Increase the Yield of Reassortant Candidate Vaccine Viruses. J Virol 2019, 93(2) http://dx.doi.org/10.1128/JVI.01551-18 
52. Jenkins A, Govind S, Morris C, Berry N: Complete Genome Sequence of Original Material Used To Derive the WHO International Standard for Human Polyomavirus BK DNA. Microbiol Resour Announc 2019, 8(43) http://dx.doi.org/10.1128/MRA.00911-19 
53. Jenkins PV, Bowyer A, Burgess C, Gray E, Kitchen S, Murphy P, Platton S, Riddell A, Chowdary P, Lester W: Laboratory coagulation tests and emicizumab treatment A United Kingdom Haemophilia Centre Doctors’ Organisation guideline. Haemophilia 2019,  http://dx.doi.org/10.1111/hae.13903 
54. Kaminski RW, Pasetti MF, Aguilar AO, Clarkson KA, Rijpkema S, Bourgeois AL, Cohen D, Feavers I, MacLennan CA: Consensus Report on Shigella Controlled Human Infection Model: Immunological Assays. Clin Infect Dis 2019, 69(Supplement_8):S596-S601 http://dx.doi.org/10.1093/cid/ciz909 
55. Kempster SL, Almond N, Dimech W, Grangeot-Keros L, Huzly D, Icenogle J, El Mubarak HS, Mulders MN, Nubling CM: WHO international standard for anti-rubella: learning from its application. Lancet Infect Dis 2019,  http://dx.doi.org/10.1016/S1473-3099(19)30274-9 
56. Kempster SL, Dougall T, Morris C, Gonzalez-Escobar G, Almond N, Anderson R: Utility of reference materials for Zika Virus nucleic acid testing. Biologicals 2019, 61:55-60 http://dx.doi.org/10.1016/j.biologicals.2019.06.007 
57. Kim JH, Alderton A, Benvenisty N, Brandsten C, Firpo M, Harrison PW, Kawamata S, Kawase E, Kurtz A, Loring JF et al: A report from a workshop of the International Stem Cell Banking Initiative, held in collaboration GAiT and the Harvard Stem Cell Institute, Boston 2017. Stem Cells 2019,  http://dx.doi.org/10.1002/stem.3003
58. Kim JH, Alderton A, Crook JM, Benvenisty N, Brandsten C, Firpo M, Harrison PW, Kawamata S, Kawase E, Kurtz A et al: A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017. Stem Cells 2019, 37(9):1130-1135 http://dx.doi.org/10.1002/stem.3003 
59. Komorowicz E, Balazs N, Tanka-Salamon A, Varga Z, Szabo L, Bota A, Longstaff C, Kolev K: Biorelevant polyanions stabilize fibrin against mechanical and proteolytic decomposition: Effects of polymer size and electric charge. J Mech Behav Biomed Mater 2019, 102:103459 http://dx.doi.org/10.1016/j.jmbbm.2019.103459 
60. Krammer F, Weir JP, Engelhardt O, Katz JM, Cox RJ: Meeting report and review: Immunological assays and correlates of protection for next-generation influenza vaccines. Influenza Other Respir Viruses 2019,  http://dx.doi.org/10.1111/irv.12706 
61. Kreuzer M, Howard C, Adhikari B, Pendry CA, Hawkins JA: Phylogenomic Approaches to DNA Barcoding of Herbal Medicines: Developing Clade-Specific Diagnostic Characters for Berberis. Front Plant Sci 2019, 10:586 http://dx.doi.org/10.3389/fpls.2019.00586 
62. Li C, Bhavaraju S, Thibeault MP, Melanson J, Blomgren A, Rundlof T, Kilpatrick E, Swann CJ, Rudd T, Aubin Y et al: Survey of peptide quantification methods and comparison of their reproducibility: A case study using oxytocin. J Pharm Biomed Anal 2019, 166:105-112 http://dx.doi.org/10.1016/j.jpba.2018.12.028 
63. Longstaff C, Locke M: Increased urokinase and consumption of alpha2 -antiplasmin as an explanation for the loss of benefit of tranexamic acid after treatment delay. J Thromb Haemost 2019, 17(1):195-205 http://dx.doi.org/10.1111/jth.14338 
64. Mancini P, Bonanno Ferraro G, Iaconelli M, Suffredini E, Valdazo-Gonzalez B, Della Libera S, Divizia M, La Rosa G: Molecular characterization of human Sapovirus in untreated sewage in Italy by amplicon-based Sanger and next-generation sequencing. J Appl Microbiol 2019, 126(1):324-331 http://dx.doi.org/10.1111/jam.14129 
65. Markey K, Asokanathan C, Feavers I: Assays for Determining Pertussis Toxin Activity in Acellular Pertussis Vaccines. Toxins (Basel) 2019, 11(7) http://dx.doi.org/10.3390/toxins11070417 
66. Markey K, Douglas-Bardsley A, Asokanathan C, Fry NK, Barkoff AM, Bacci S, Kodmon C, He Q: Improvement in serological diagnosis of pertussis by external quality assessment. J Med Microbiol 2019, 68(5):741-747 http://dx.doi.org/10.1099/jmm.0.000926 
67. Matejtschuk P, Duru C, Bristow AF, Burns CJ, Cowper B, Daas A, Costanzo A: Establishment of an erythropoietin CRS with stable measurable dimer content for SEC system suitability qualification. Pharmeur Bio Sci Notes 2019, 2019:11-26  
68. Matejtschuk P, Duru C, Malik KP, Bristow AF, Costanzo A, Burns CJ: Development of a stable chemically cross-linked erythropoietin dimer for use in the quality control of erythropoietin therapeutic products. Anal Bioanal Chem 2019, 411(13):2755-2758 http://dx.doi.org/10.1007/s00216-019-01768-4 
69. Matejtschuk P. MK, Duru C: Formulation and Process Development for Lyophilized Biological Reference Material. Lyophilization of Pharmaceuticals and Biologicals 2019, Methods in Pharmacology and Toxicology, Humana Press, New York, NY  
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71. Mattiuzzo G, Knezevic I, Hassall M, Ashall J, Myhill S, Faulkner V, Hockley J, Rigsby P, Wilkinson DE, Page M et al: Harmonization of Zika neutralization assays by using the WHO International Standard for anti-Zika virus antibody. NPJ Vaccines 2019, 4:42 http://dx.doi.org/10.1038/s41541-019-0135-3 
72. Maze EA, Ham C, Kelly J, Ussher L, Almond N, Towers GJ, Berry N, Belshaw R: Variable Baseline Papio cynocephalus Endogenous Retrovirus (PcEV) Expression Is Upregulated in Acutely SIV-Infected Macaques and Correlated to STAT1 Expression in the Spleen. Front Immunol 2019, 10:901 http://dx.doi.org/10.3389/fimmu.2019.00901 
73. McDonald JU, Rigsby P, Atkinson E, Engelhardt OG, Study P: Expansion of the 1st WHO international standard for antiserum to respiratory syncytial virus to include neutralisation titres against RSV subtype B: An international collaborative study. Vaccine 2019,  http://dx.doi.org/10.1016/j.vaccine.2019.10.095 
74. Mehler VJ, Burns C, Moore ML: Concise Review: Exploring Immunomodulatory Features of Mesenchymal Stromal Cells in Humanized Mouse Models. Stem Cells 2019, 37(3):298-305 http://dx.doi.org/10.1002/stem.2948 
75. Mekkaoui L, Ferrari M, Mattiuzzo G, Ma B, Nannini F, Onuoha S, Kotsopoulou E, Takeuchi Y, Pule M: Generation of a neutralizing antibody against RD114-pseudotyped viral vectors. J Gen Virol 2019,  http://dx.doi.org/10.1099/jgv.0.001309 
76. Metcalfe C: A Proteomics Workflow for the Identification of Labile Disulphide Bonds at the Cell Surface. Methods Mol Biol 2019, 1967:21-43 http://dx.doi.org/10.1007/978-1-4939-9187-7_3 
77. Metcalfe C, Dougall T, Bird C, Rigsby P, Behr-Gross ME, Wadhwa M, Study POT: The first World Health Organization International Standard for infliximab products: A step towards maintaining harmonized biological activity. MAbs 2019, 11(1):13-25 http://dx.doi.org/10.1080/19420862.2018.1532766 
78. Mohring F, Hart MN, Rawlinson TA, Henrici R, Charleston JA, Diez Benavente E, Patel A, Hall J, Almond N, Campino S et al: Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research. Elife 2019, 8 http://dx.doi.org/10.7554/eLife.45829 
79. Morris C, Govind S, Fryer J, Almond N: SoGAT-25 years of improving the measurement of nucleic acids in infectious disease diagnostics. Metrologia 2019, 56(4) http://dx.doi.org/ARTN 044007 
80. Munis AM, Mattiuzzo G, Bentley EM, Collins MK, Eyles JE, Takeuchi Y: Use of Heterologous Vesiculovirus G Proteins Circumvents the Humoral Anti-envelope Immunity in Lentivector-Based In Vivo Gene Delivery. Mol Ther Nucleic Acids 2019, 17:126-137 http://dx.doi.org/10.1016/j.omtn.2019.05.010 
81. New RRC, Moore BD, Butcher W, Mahood R, Lever MS, Smither S, O’Brien L, Weller SA, Bayliss M, Gibson LCD et al: Antibody-mediated protection against MERS-CoV in the murine model. Vaccine 2019, 37(30):4094-4102 http://dx.doi.org/10.1016/j.vaccine.2019.05.074 
82. O’Connor DJ, Buckland J, Almond N, Boyle J, Coxon C, Gaki E, Martin J, Mattiuzzo G, Metcalfe C, Page M et al: Commonly setting biological standards in rare diseases. Expert Opinion on Orphan Drugs 2019, 7(7-8):305-314 http://dx.doi.org/10.1080/21678707.2019.1652598 
83. Oddone I, Arsiccio A, Duru C, Malik K, Ferguson J, Pisano R, Matejtschuk P: Vacuum-Induced Surface Freezing for the Freeze-Drying of the Human Growth Hormone: How Does Nucleation Control Affect Protein Stability? J Pharm Sci 2019,  http://dx.doi.org/10.1016/j.xphs.2019.04.014 
84. Odevall L R, S, Smith, D, Wu T, Qadri F, Holmgren, J, Lynch, J, Pavliak, V: Consensus Meeting on International Standards for Oral Whole Cell Killed Cholera Vaccines, 17-18 May 2018, Seoul, Republic of Korea. VACCINATION RESEARCH Open Journal 2019, 1(1):72-78 http://dx.doi.org/10.17140/VROJ-1-112 
85. Piccoli S, Mehta D, Vitaliti A, Allinson J, Amur S, Eck S, Green C, Hedrick M, Hopper S, Ji A et al: 2019 White Paper on Recent Issues in Bioanalysis: FDA Immunogenicity Guidance, Gene Therapy, Critical Reagents, Biomarkers and Flow Cytometry Validation (Part 3 - Recommendations on 2019 FDA Immunogenicity Guidance, Gene Therapy Bioanalytical Challenges, Strategies for Critical Reagent Management, Biomarker Assay Validation, Flow Cytometry Validation & CLSI H62). Bioanalysis 2019, 11(24):2207-2244 http://dx.doi.org/10.4155/bio-2019-0271 
86. Proudfoot A, Wadhwa M: WHO International Standards and reference preparations for cytokines and growth factors. Cytokine 2019, 123:154797 http://dx.doi.org/10.1016/j.cyto.2019.154797 
87. Proudfoot AEI, Wadhwa M: WHO International Standards and Reference Preparations for Cytokines and Growth Factors. J Interferon Cytokine Res 2019, 39(7):438-439 http://dx.doi.org/10.1089/jir.2019.0078 
88. Ramage W, Gaiotto T, Ball C, Risley P, Carnell GW, Temperton N, Cheung CY, Engelhardt OG, Hufton SE: Cross-Reactive and Lineage-Specific Single Domain Antibodies against Influenza B Hemagglutinin. Antibodies (Basel) 2019, 8(1) http://dx.doi.org/10.3390/antib8010014 
89. Rampling T, Page M, Horby P: International Biological Reference Preparations for Epidemic Infectious Diseases. Emerging Infectious Diseases 2019, 25(2):205-211 http://dx.doi.org/10.3201/eid2502.180798 
90. Riches-Duit R, Hassall L, Rigsby P, Stickings P: Evaluation of a capture antigen ELISA for the characterisation of tetanus vaccines for veterinary use. Biologicals 2019, 61:8-14 http://dx.doi.org/10.1016/j.biologicals.2019.08.003 
91. Robinson MJ, Matejtschuk P, Longstaff C, Dalby PA: Selective Stabilization and Destabilization of Protein Domains in Tissue-Type Plasminogen Activator Using Formulation Excipients. Mol Pharm 2019, 16(2):744-755 http://dx.doi.org/10.1021/acs.molpharmaceut.8b01024 
92. Rudd TR, Mauri L, Marinozzi M, Stancanelli E, Yates EA, Naggi A, Guerrini M: Multivariate analysis applied to complex biological medicines. Faraday Discuss 2019, 218(0):303-316 http://dx.doi.org/10.1039/c9fd00009g 
93. Ruscic J, Perry C, Mukhopadhyay T, Takeuchi Y, Bracewell DG: Lentiviral Vector Purification Using Nanofiber Ion-Exchange Chromatography. Mol Ther Methods Clin Dev 2019, 15:52-62 http://dx.doi.org/10.1016/j.omtm.2019.08.007 
94. Saraiva L, Wang L, Kammel M, Kummrow A, Atkinson E, Lee JY, Yalcinkaya B, Akgoz M, Hockner J, Ruf A et al: Comparison of Volumetric and Bead-Based Counting of CD34 Cells by Single-Platform Flow Cytometry. Cytometry B Clin Cytom 2019, 96(6):508-513 http://dx.doi.org/10.1002/cyto.b.21773 
95. Shaw HA, Khodadoost L, Preston MD, Corver J, Mullany P, Wren BW: Clostridium difficile clade 3 (RT023) have a modified cell surface and contain a large transposable island with novel cargo. Sci Rep 2019, 9(1):15330 http://dx.doi.org/10.1038/s41598-019-51628-5 
96. Shaw HA, Preston MD, Vendrik KEW, Cairns MD, Browne HP, Stabler RA, Crobach MJT, Corver J, Pituch H, Ingebretsen A et al: The recent emergence of a highly related virulent Clostridium difficile clade with unique characteristics. Clin Microbiol Infect 2019,  http://dx.doi.org/10.1016/j.cmi.2019.09.004 
97. Studholme L, Sutherland J, Desai T, Hockley J, Care R, Nordgren IK, Vipond C, Collaborative Study G: Evaluation of the monocyte activation test for the safety testing of meningococcal B vaccine Bexsero: A collaborative study. Vaccine 2019, 37(29):3761-3769 http://dx.doi.org/10.1016/j.vaccine.2018.05.073 
98. Taylor SL, Hogwood J, Guo W, Yates EA, Turnbull JE: By-Products of Heparin Production Provide a Diverse Source of Heparin-like and Heparan Sulfate Glycosaminoglycans. Sci Rep 2019, 9(1):2679 http://dx.doi.org/10.1038/s41598-019-39093-6 
99. Thaventhiran T, Wong W, Alghanem AF, Alhumeed N, Aljasir MA, Ramsey S, Sethu S, Yeang HXA, Chadwick AE, Cross M et al: CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program. Monoclon Antib Immunodiagn Immunother 2019, 38(2):60-69 http://dx.doi.org/10.1089/mab.2018.0042 
100. Thelwell C, Hogwood J, Daniels S, Rigsby P: A new WHO Reference Reagent for Activated Blood Coagulation Factor X (FXa), Human (15/102). J Thromb Haemost 2019,  http://dx.doi.org/10.1111/jth.14623 
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102. van den Besselaar A, van Rijn CJJ, Hubbard AR, Kitchen S, Tripodi A, Cobbaert CM: Requirement of a reference measurement system for the tissue factor-induced coagulation time and the international normalized ratio. Clin Chem Lab Med 2019, 57(7):e169-e172 http://dx.doi.org/10.1515/cclm-2018-1194 
103. Vipond C, Sutherland J, Nordgren K, Kemp G, Heath A, Care R, Studholme L: Development and validation of a monocyte activation test for the control/safety testing of an OMV-based meningococcal B vaccine. Vaccine 2019, 37(29):3747-3753 http://dx.doi.org/10.1016/j.vaccine.2018.06.038 
104. Wadhwa M, Thorpe R: Bioanalytical strategies in determining immunogenicity. Bioanalysis 2019, 11(17):1535-1537 http://dx.doi.org/10.4155/bio-2019-0233 
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106. Wan H, Gao J, Yang H, Yang S, Harvey R, Chen YQ, Zheng NY, Chang J, Carney PJ, Li X et al: The neuraminidase of A(H3N2) influenza viruses circulating since 2016 is antigenically distinct from the A/Hong Kong/4801/2014 vaccine strain. Nat Microbiol 2019, 4(12):2216-2225 http://dx.doi.org/10.1038/s41564-019-0522-6 
107. Wang Y, Tatham MH, Schmidt-Heck W, Swann C, Singh-Dolt K, Meseguer-Ripolles J, Lucendo-Villarin B, Kunath T, Rudd TR, Smith AJH et al: Multiomics Analyses of HNF4alpha Protein Domain Function during Human Pluripotent Stem Cell Differentiation. iScience 2019, 16:206-217 http://dx.doi.org/10.1016/j.isci.2019.05.028 
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109. Whiting G, Vipond C, Facchetti A, Chan H, Wheeler JX: Measurement of surface protein antigens, PorA and PorB, in Bexsero vaccine using quantitative mass spectrometry. Vaccine 2019,  http://dx.doi.org/10.1016/j.vaccine.2019.11.082 

 
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2. Adhya D, Annuario E, Lancaster MA, Price J, Baron-Cohen S, Srivastava DP: Understanding the role of steroids in typical and atypical brain development: Advantages of using a "brain in a dish" approach. J Neuroendocrinol 2018, 30(2) http://dx.doi.org/10.1111/jne.12547
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9. Claessens A, Harris LM, Stanojcic S, Chappell L, Stanton A, Kuk N, Veneziano-Broccia P, Sterkers Y, Rayner JC, Merrick CJ: RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics. PLoS genetics 2018, 14(7):e1007490 http://dx.doi.org/10.1371/journal.pgen.1007490
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12. Cowper B, Li X, Yu L, Zhou Y, Fan WH, Rao CM: Comprehensive glycan analysis of twelve recombinant human erythropoietin preparations from manufacturers in China and Japan. J Pharm Biomed Anal 2018, 153:214-220 http://dx.doi.org/10.1016/j.jpba.2018.02.043
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29. Green LR, Lucidarme J, Dave N, Chan H, Clark S, Borrow R, Bayliss CD: Phase Variation of NadA in Invasive Neisseria meningitidis Isolates Impacts on Coverage Estimates for 4C-MenB, a MenB Vaccine. J Clin Microbiol 2018, 56(9) http://dx.doi.org/10.1128/JCM.00204-18
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2016

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