Research grade stem cell lines

    The UK Stem Cell Bank provides extensive quality control on available research-grade human stem cell lines. This includes tests to ensure the safety (sterility and mycoplasma), identity (STR profile), and potency (gene profile) of the cell lines. A Certificate of Analysis is provided with each order. The UK Stem Cell Bank also offers technical advice and cell line information to support customers in choosing the most appropriate cell line for their research. 

    To obtain cell lines, visit our Apply for Stem Cell Lines page.

    If you have any queries, please do not hesitate to get in touch at: enquiriesmail@mhra.gov.uk.

    Cell Line

    Usage

    Availability

    Feeder Status

    UK Steering Committee Numberr

    UK Stem Cell Bank Accession Number

     Cell Type

    Karyotype

    Depositor

    Country 

    More Information

    MasterShef11 Research / Pre-clinical Available Feeder Free SCSC13-06 C-16-021 Human Embryonic 46XY University of Sheffield UK https://hpscreg.eu/cell-line/UOSe015-A 
    RC11 Research / Pre-clinical Available Feeder Free SCSC11-02 C-18-038 Human Embryonic 46XX University of Edinburgh UK https://hpscreg.eu/cell-line/UOSe015-A 
    RC17 Research / Pre-clinical Available Feeder Free SCSC11-38 C-18-044 Human Embryonic 46XX[30] University of Edinburgh UK https://hpscreg.eu/cell-line/RCe015-A 
    BJNhem19 Research only Available Feeder Dependent SCSC07-43 R-08-022 Human Embryonic 46XY JNCASR, Bangalore India https://hpscreg.eu/cell-line/JNCSRe001-A 
    BJNhem20 Research only Available Feeder Dependent SCSC07-43 R-08-021 Human Embryonic 46XX JNCASR, Bangalore India https://hpscreg.eu/cell-line/JNCSRe002-A 
    Edi2 Research only Available Feeder Dependent SCSC07-12 R-07-023 Human Embryonic 46XX[20] University of Edinburgh UK https://hpscreg.eu/cell-line/EDe009-A 
    Edi4 Research only Available Feeder Dependent SCSC07-13 R-07-025 Human Embryonic 46XY University of Edinburgh UK https://hpscreg.eu/cell-line/EDe011-A 
    KCL002(WT4) Research only Available Feeder Dependent SCSC05-09 R-06-028 Human Embryonic 47XY,+7[11] / 48XY,+7,+20[1] / 46XY[8] King’s College London UK https://hpscreg.eu/cell-line/KCLe002-A 
    KCL003(CF1) Research only Available Feeder Dependent SCSC05-10 R-06-027 Human Embryonic 46XY[20] King’s College London UK https://hpscreg.eu/cell-line/KCLe003-A 
    KCL009(trans-1) Research only Available Feeder Dependent SCSC07-49 R-08-011 Human Embryonic Female King’s College London UK https://nibsc.org/linkhandler.ashx?pid=4297 
    KCL031 Research only Available Feeder Free SCSC11-58-(d) C-16-011 Human Embryonic 46XY[30] King’s College London UK X
    KCL033 Research only Available Both SCSC11-54 C-16-013 Human Embryonic 46XX King’s College London UK X
    KCL034 Research only Available Feeder Free SCSC11-54 C-16-014 Human Embryonic 46XY King’s College London UK X
    KCL037 Research only Available Feeder Dependent SCSC11-58-(d) C-16-015 Human Embryonic 46XY[30] King’s College London UK X
    MAN01 Research only Available Feeder Dependent SCSC08-02 R-08-017 Human Embryonic 46XX University of Manchester UK https://hpscreg.eu/cell-line/UMANe001-A 
    MAN02 Research only Available Feeder Dependent SCSC09-01 R-09-011 Human Embryonic 46XX[20] University of Manchester UK https://hpscreg.eu/cell-line/CMFTe001-A 
    MAN16 Research only Available Feeder Free SCSC14-25 C-16-008 Human Embryonic 46XY University of Manchester UK X
    MasterShef02 Research only Available Feeder Dependent SCSC12-03 C-14-021 Human Embryonic 45X-X University of Sheffield UK https://hpscreg.eu/cell-line/UOSe007-A 
    MasterShef04 Research only Available Feeder Free SCSC12-05 C-14-023 Human Embryonic 46XY University of Sheffield UK https://hpscreg.eu/cell-line/CMFTe004-A 
    MasterShef07 Research only Available Feeder Dependent SCSC17-20 C-16-019 Human Embryonic 46XY University of Sheffield UK https://hpscreg.eu/cell-line/UMANe004-A 
    NCL01 Research only Available Feeder Dependent SCSC04-01 R-05-013 Human Embryonic 46XX[10] Newcastle University UK https://hpscreg.eu/cell-line/UNEWe001-A 
    NCL02 Research only Available Feeder Dependent SCSC06-46 R-07-014 Human Embryonic 46XX[20] Newcastle University UK https://hpscreg.eu/cell-line/UNEWe002-A 
    NCL03 Research only Available Feeder Dependent SCSC06-46 R-07-015 Human Embryonic 46XX[20] Newcastle University UK https://hpscreg.eu/cell-line/UNEWe003-A 
    NCL04 Research only Available Feeder Dependent SCSC06-46 R-07-016 Human Embryonic 46XY Newcastle University UK https://hpscreg.eu/cell-line/UNEWe004-A 
    NCL05 Research only Available Feeder Dependent SCSC06-46 R-07-017 Human Embryonic 46XX Newcastle University UK https://hpscreg.eu/cell-line/UNEWe005-A
    NOTT1 Research only Unavailable (Rebanking) Feeder Dependent SCSC06-12 R-07-001 Human Embryonic 46XX University of Nottingham UK https://hpscreg.eu/cell-line/UNOTe001-A 
    NOTT2 Research only Unavailable (Rebanking) Feeder Dependent SCSC06-31 R-07-002 Human Embryonic 46XY[8] University of Nottingham UK https://hpscreg.eu/cell-line/UNOTe002-A 
    OXF2 Research only Unavailable (Rebanking) Feeder Dependent SCSC10-18-(b) R-11-002 Human Embryonic Female University of Oxford UK https://nibsc.org/linkhandler.ashx?pid=4308 
    Shef1 Research only Unavailable (Rebanking) Feeder Dependent SCSC04-23 R-05-007 Human Embryonic 46XY[8] Tenpoint Therapeutics Ltd UK https://hpscreg.eu/cell-line/AXORe001-A 
    Shef2 Research only Unavailable (Rebanking) Feeder Dependent SCSC04-23 R-05-027 Human Embryonic 46XX[20] Pfizer UK https://hpscreg.eu/cell-line/AXORe002-A 
    Shef3 Research only Unavailable (Rebanking) Feeder Dependent SCSC04-24 R-05-008 Human Embryonic 46XX[20] University of Sheffield UK https://hpscreg.eu/cell-line/UOSe003-A 
    Shef6 Research only Unavailable (Rebanking) Both SCSC05-23 R-05-031 Human Embryonic 46XX[30] University of Sheffield UK https://hpscreg.eu/cell-line/UOSe006-A 
    Shef7 Research only Unavailable (Rebanking) Both SCSC06-30 R-07-004 Human Embryonic 46XX University College London UK https://hpscreg.eu/cell-line/AXORe007-A 
    Shef8 Research only Unavailable (Rebanking) Feeder Dependent SCSC07-28 R-08-015 Human Embryonic 46XX Pfizer UK https://nibsc.org/linkhandler.ashx?pid=4314 
       Tier 1                             The alteration has well-established published evidence confirming clinical utility in this tumour type, in at least one of the following contexts: predicting response to treatment with an FDA-approved therapy; strongly supportive in establishing a definitive diagnosis; assessing prognosis; or conferring an inherited increased risk of cancer to this patient and family.
       Tier 2 The alteration may have clinical utility in at least one of the following contexts: selection of an investigational therapy in clinical trials for this cancer type; limited evidence of prognostic association; supportive of a specific diagnosis; proven association of response to treatment with an FDA-approved therapy in a different type of cancer; or similar to a different mutation with a proven association with response to treatment with an FDA-approved therapy in this type of cancer.
       Tier 3 The alteration is of uncertain clinical utility, but may have a role as suggested by at least one of the following: demonstration of association with response to treatment in this cancer type in preclinical studies (e.g., in vitro studies or animal models); alteration in a biochemical pathway that has other known, therapeutically-targetable alterations; alteration in a highly conserved region of the protein predicted, in silico, to alter protein function; or selection of an investigational therapy for a different cancer type.
       Tier 4 The alteration is novel, or its significance has not been studied in cancer. A subset of these alterations likely represents normal germline variants as the assay is not analysed in conjunction with a matched normal from the same patient.
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