NIBSC - Product details

ID	0145
Title	184V (3TC/FTC Resistant)
Characteristics	In HeLa CD4+ cell assay this virus has an IC50 value for 3TC and FTC around 1000 fold that of the wild type parental virus HXB2. Derived by co-transfection of MT-2 cells with M13 RT clone containing 184V plus RT deleted proviral clone pHIVdRTBstEII
Source	Dr B Larder and Dr S Kemp
Reference	Tisdale et al (1993) Proc Natl Acad Sci (USA)