*Dear Customer, You will notice that this reagent has been filled in glass ampoules instead of the usual glass vials. This will not have any impact on its binding properties.In case of ampoule breakage during shipment, use absorbent material wetted with an appropriate disinfectant to take up ampoule content and clean the surface of intact ampoules. Rinse then with water. Absorbent materials used to treat spillage should be treated as biological waste according to your local procedures. Unbroken ampoules will be still suitable for use. Kind Regards, NIBSC TeamPlease follow the “directions for opening” in section 6 of the instructions for use. Once opened, we recommend transferring the ampoule contents to suitable container for ongoing use and storage.should be treated as biological waste according to your local procedures. Unbroken ampoules will be still suitable for use.