Dr Mark Preston joined the NIBSC as a bioinformatician in 2015, with 17 years of experience in academia and industry applying mathematical analysis, statistics and modelling for biological, financial and engineering systems. In 2016 he established the Institute’s Core NGS and Bioinformatics facility within the Division of Analytical Sciences to strengthen the capability for genomic research at the NIBSC, and in the process creating a core team of sequencing scientists and bioinformaticians. Using a vast array of mathematical, statistical and computational tools, Dr Preston’s aim is to broaden our understanding of biological systems, with a focus on the analysis of next generation sequencing data. His research includes the publication of over 20 peer-reviewed journal articles and the development of multiple open-source software packages.
Dr Preston’s research interests lie in the development of improved sensitivity analysis in NGS data for applications in diagnostics and the development of biological standards; including for vaccines, adventitious agent detection and use in clinical settings. He aims to optimise practises in NGS analysis and encourage the application of NGS as a powerful tool for clinical research. As such he works with a number of interdisciplinary groups across the NIBSC, within the MHRA and the wider diagnostic community.
Head of Bioinformatics/NGS
1998: BSc Mathematics, University of Bath2000: MSc Multimedia Technology, University of Bath2007: PhD, Mathematics, University of Reading